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Alternative Energy Accessories
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CystineCystine is the amino acid dimer formed when a pair of cysteine molecules are joined by a disulfide bond.
It is described by the formula (SCH2CH(NH2)CO2H)2. It is a colorless solid, and melts at 247-249 °C.
It was discovered in 1810 by William Hyde Wollaston but was not recognized as a component of proteins until it was isolated from the horn of a cow in 1899.
Through formation of disulfide bonds within and between protein molecules, cystine is a significant determinant of the tertiary structure of most proteins.
Disulfide bonding, along with hydrogen bonding and hydrophobic interactions is partially responsible for the formation of the gluten matrix in bread.
Human hair contains approximately 5% cystine by mass. PropertiesThe disulfide link is readily reduced to give the corresponding thiol, cysteine.
This reaction is typically effected with thiols such as mercaptoethanol or dithiothreitol.
Nutritional sourcesSupplemental N-acetyl cysteine is claimed to be a source of cystine, but the dose of this supplement is limited by side effects.
One of the richest nutritional sources of cystine in the diet is undenatured whey proteins from milk.
The disulfide-bonded cystine is not digested or significantly hydrolized by the stomach, but is transported by the blood stream to the tissues of the body.
Here, within the cells of the body, the weak disulfide bond is cleaved to give cysteine, from which glutathione can be synthesized. In animal feedDisulfide bonds can be broken at temperatures above about 150 °C, especially at low moisture levels (below about 20%). Side effectsNutritional sources of cystine are virtually free of the toxic side effects associated with the single molecule of cysteine, N-acetyl cysteine. The greatest dietary source of cystine is bio-active, unpasteurized or low-heat pasteurized undenatured whey proteins. *
* Read the complete Article in Wikipedia, Feb 22, 2009 * Cystine. (2009, January 24). In Wikipedia,The Free Encyclopedia.Retrieved 16:10, February 23, 2009, fromhttp://en.wikipedia.org/w/index.php?title=Cystine&oldid=266116450______________________
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Disclaimer : In accordance with FDA regulation, we do not make any therapeutic claims for any Dietary Supplements in accordance with the Dietary Supplement Health and Education Act. Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physicians, health care professional or other professional. You should not use the information on this website for diagnosing or treating any health problem, symptom or disease, prescribing any medication or other treatment, or in place of any other professional advice. This information is not intended to diagnose, treat, cure or prevent any diseases. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Your discretion is advised. Copyright © 2007
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