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Folic Acid or Vitamin B9..Folate

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folate in peas

Folic Acid or Folate..Vitamin B9

 Folic Acid or Folate..or Vitamin B9..is a brain food and helps in: energy production; strengthens immunity; proper formation and functioning of the white blood cells; RNA and DNA synthesis; cell division; cell replication; and protein metabolism....Deficiencies: anemia, graying hair, fatigue, insomnia, memory problems.

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Folic Acid is essential for: production of red blood cells, tissue cells, normal growth, healthy intestinal tract and prenatal nourishment.

Folate folate in dried beans in Dried Beans

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Folic Acid is a member of the B-complex family which play a role in energy production and the formation of red blood cells.

Folate folate in spinach in Spinach

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Folic Acid may be helpful for the immune system, fatigue, birth defect prevention.

Folate folate in turnip greens in Turnip Greens

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It is important for cell division and replication.

Folate folate in grains and cereals in Grains and Cereals

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Folic Acid is a B vitamin and a crucial nutrient for the health of the heart and normal fetus development.

Folate folate in peas in Peas

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Folic acid is a methyl donor needed to reduce homocysteine back to methionine and for accurate synthesis of DNA and normal cell division throughout life including during pregnancy.

Folate folate in bakers yeast in Bakers Yeast

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Healthful diets with adequate folic acid may reduce a woman’s risk of having a child with certain brain or spinal cord defects.

Folate folate in beef liver in Beef Liver

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Folic Acid, along with vitamin B-12, is required for the synthesis of DNA, the principal genetic material in the body.

Folate folate in sunflowers seeds in Sunflower Seeds folate in sunflower seedsfolate in sunflower seeds photo with shell

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Folate helps prevent neural tube defects in developing embryos, making it an important nutritional supplement for women who are, or intend to become, pregnant.

 

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Folate..Folic Acid..Vitamin B9

From The Article In Wikipedia... Jan 24, 2009

Folic acid (also known as Vitamin M and Folacin) and Folate (the anionic form) are forms of the water-soluble Vitamin B9.

These occur naturally in food and can also be taken as supplements.

Folate in foods and other sources

Leafy vegetables such as spinach, turnip greens, lettuces, dried beans and peas, fortified cereal products, sunflower seeds and certain other fruits and vegetables are rich sources of folate.

Liver and liver products also contain high amounts of folate, as does bakers yeast.

Some breakfast cereals (ready-to-eat and others) are fortified with 25% to 100% of the recommended dietary allowance (RDA) for folic acid.

A table of selected food sources of folate and folic acid can be found at the USDA National Nutrient Database for Standard Reference....{Mother has inserted a link here to go to the page, to find out what you might like...if you click on the blue circle with the A on it, at the quality you want to measure(like magnesium for instance)...it will take you to another page showing a HUGE list of foods with the quantity of magnesium in each one of them...} http://www.ars.usda.gov/Services/docs.htm?docid=22114

Folate is also found in Vegemite or Marmite, with an average serving (5g) containing 100μg or 2000μg per 100g.

Dr. Lucy Wills demonstrated that anemia could be reversed with brewer's yeast.

Folate was identified as the corrective substance in brewer's yeast in the late 1930s and was first isolated in pure form from spinach leaves by Mitchell and others in 1941.

DNA and cell division

Folate is necessary for the production and maintenance of new cells.

This is especially important during periods of rapid cell division and growth such as infancy and pregnancy.

Folate is needed to synthesize DNA bases (most notably thymine, but also purine bases) needed for DNA replication.

Thus folate deficiency hinders DNA synthesis and cell division, affecting most notably bone marrow and cancer, both of which participate in rapid cell division.

RNA transcription, and subsequent protein synthesis, are less affected by folate deficiency as the mRNA can be recycled and used again (as opposed to DNA synthesis where a new genomic copy must be created).

Since folate deficiency limits cell division, erythropoiesis, production of red blood cells (RBCs) is hindered and leads to megaloblastic anemia which is characterized by large immature RBCs.

This pathology results from persistently thwarted attempts at normal DNA replication, DNA repair, and cell division and produces abnormally large cells (megaloblasts) with abundant cytoplasm capable of RNA and protein synthesis but with clumping and fragmentation of nuclear chromatin.

Some of these large cells, although immature, are released early from the marrow in an attempt to compensate for the anemia caused by lack of RBCs.

Both adults and children need folate to make normal RBCs and prevent anemia.

Deficiency of folate in pregnant women has been implicated in neural tube defects; therefore, many cereals sold in developed countries are enriched with folate to avoid such complications.

A number of drugs interfere with the biosynthesis of folic acid and THF.

Among them are the dihydrofolate reductase inhibitors such as trimethoprim, pyrimethamine and methotrexate; the sulfonamides (competitive inhibitors of para-aminobenzoic acid in the reactions of dihydropteroate synthetase).

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Recent research has shown that it is also very important for men who are planning on fathering children, reducing chromosomal defects in their sperm.

In 1996, the United States Food and Drug Administration (FDA) published regulations requiring the addition of folic acid to enriched breads, cereals, flours, corn meals, pastas, rice, and other grain products.

This data indicates that since the addition of folic acid in grain-based foods as mandated by the Food and Drug Administration, the rate of neural tube defects dropped by 25% in the United States.

Although folic acid does reduce the risk of birth defects, it is only one part of the picture and should not be considered a cure.

Even women taking daily folic acid supplements have been known to have children with neural tube defects.

However a 2005 study found that 5 mg. of folate daily over a three-week period reduced pulse pressure by 4.7 mmHg. compared with a placebo, and concluded that.....

"Folic acid is a safe and effective supplement that targets large artery stiffness and may prevent isolated systolic hypertension."

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Also, as a result of new research, "heart experts" at Johns Hopkins Medical Center reported in March 2008 in favour of therapeutic folate, although they cautioned that it is premature for people to begin to self-medicate by taking high doses of folic acid."

Depression

Some evidence links a shortage of folate with depression.

There is some limited evidence from randomised controlled trials that using folic acid in addition to antidepressant medication , specifically SSRIs, may have benefits.

Memory and mental agility

In a 3-year trial on 818 people over the age of 50, short-term memory, mental agility and verbal fluency were all found to be better among people who took 800 micrograms of folic acid daily ( twice the current RDA ) than those who took placebo.

The study was reported in The Lancet on 19 January 2007.

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However one recent study has demonstrated that high folic or folate levels when combined with low B12 levels are associated with significant cognitive impairment among the elderly.

In any case, it is important for older adults to be aware of the relationship between folic acid and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency.

If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains folic acid.

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* Read an Article in Wikipedia, Jan 24, 2009

Read an article in Wikipedia with references and links Jan 2, 2012

** Folic acid. (2011, December 20). In Wikipedia, The Free Encyclopedia.

Retrieved 19:51, January 2, 2012, from

http://en.wikipedia.org/w/index.php?title=

Folic_acid&oldid=466841020

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Folate..folic acid..vitamin B9

Folate is necessary for the production and maintenance of new cells.

This is especially important during periods of rapid cell division and growth such as infancy and pregnancy.

Folate is needed to synthesize DNA bases (most notably thymine, but also purine bases) needed for DNA replication.

Thus folate deficiency hinders DNA synthesis and cell division, affecting most notably bone marrow and cancer, both of which participate in rapid cell division.

 DEFICIENCIES: sore red tongue, anemia, apathy, digestive disturbances, fatigue, graying hair, growth impairment, insomnia, labored breathing, memory problems, paranoia, weakness, birth defects in offspring. [2]


      SOURCES: asparagus, barley, beef, bran, brewer's yeast, brown rice, cheese, chicken, dates, green leafy vegetables, lamb, legumes, lentils, milk, liver, whole wheat, whole grains, salmon, tuna, wheat germ, root vegetables pork, oranges, split peas, mushrooms. [3]

The Vitamin B Complex

....and as you will find in any nutritional healing book as well as Prescription for Nutritional Healing by Phyllis A Balch, the B Vitamins are necessary for the maintenance of certain physiological functions and systems including, the nerves, eyes, hair, skin, mouth, liver, proper brain function and healthy gastrointestinal muscle tone.


The entire complex of B vitamins is necessary for energy production.  They are called coenzymes because they help the chemical reactions of enzymes with many other substances. 

B-complex vitamins are necessary for the relief of anxiety and depression. 

Elderly people need an adequate intake of the B vitamins as well as other vitamins because as we age we do not properly absorb nutrients. 

There have been cases of elderly people diagnosed with Alzheimer's disease whose symptoms were relieved with the proper intake of Vitamin B-12 plus the B-Complex to relieve their depletion of these vitamins. 

The B vitamins work properly as a team but one can take more of some than others.
A deficiency in one B vitamin often indicates a deficiency in another. 

Although the B vitamins work in concert with each other, they will be discussed individuallly.

Most adults do not consume adequate amounts of folate.

Sincerely, Mother

 

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See references for complete information including notes, comments, complete symptoms, sources, concerns and cautions.

Disclaimer :

In accordance with FDA regulation, we do not make any therapeutic claims for any Dietary Supplements in accordance with the Dietary Supplement Health and Education Act.

Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physicians, health care professional or other professional. You should not use the information on this website for diagnosing or treating any health problem, symptom or disease, prescribing any medication or other treatment, or in place of any other professional advice. This information is not intended to diagnose, treat, cure or prevent any diseases. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Your discretion is advised.

Copyright © 2007

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