Human case reports and results from laboratory and animal studies show that..Grape seed extract..may be useful to treat heart diseases such as high blood pressure and high cholesterol.

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Grape Seed

A dietary supplement to support immune system and circulatory functions and proper skin health.

oligomeric proanthocyanidins (OPCs) -

OPCs are a special class of water soluble bioflavonoids that are potent antioxidants.

In some comparative tests, OPCs were found to be 50 times more potent than Vitamin E and 20 times more potent than Vitamin C.

OPCs prevent the release of histamine from mast cells thereby reducing the adverse effects of histamine.

OPCs support capillary strength.

Weak capillaries can contribute to bruising, elastin and collagen dysfunction, edema and circulatory insufficiencies.

Grapeseed grape seed illustration Illustration

Grape Seed Extract formula can provide powerful protection from two sources

1. a natural red grape seed extract rich in the plant based antioxidants called proanthocyanidins OPCs.

2. Resveratrol from grape skin

Grapeseed grape seed oil Oil

See All of Mother's Other Oils ... and more ... and even more ...

Grapeseed Oil is a light, odorless natural oil derived from Italian grape seeds.

It has emolient properties that impart a rich, silky luster to skin while soothing skin irritation.

This oil is suitable for all skin types and will not aggravate acne because of its mild astringent properties.

Grape Seed Oil is an excellent base for lotions and is also useful for hair conditioning and styling.

This 100% pure oil is also food grade and can be used as a salad or culinary oil.

Grapeseed grapes Grapes

Source Naturals Grape Seed Extract is a rich source of procyanidins – water soluble antioxidant flavonoids that are excellent free radical scavengers and have been shown to support the capillaries and circulatory health.

Grape seed extract also has been shown in preliminary research to cross the blood/brain barrier and provide powerful antioxidant protection to the brain.

Grape Seed Extract is a rich source of bioflavonoids.

Well tolerated by most highly allergic individuals.

Grapeseed Grape Flowers

Grape seed is a dietary supplement that supports the immune system, circulatory functions and proper skin health.

Grape Seed Extract, from juice grapes, Vitis vinifera, yield a higher percentage of oligomeric proanthocyanidins OPCs) than unconcentrated grape seed powder.

OPCs are a special class of water soluble bioflavonoids that are potent antioxidants. In some comparative tests, OPCs were found to be 50 times more potent than Vitamin E and 20 times more potent than Vitamin C.

Proanthocyanidins—also called ''OPCs'' for oligomeric procyanidins or ''PCOs'' for procyanidolic oligomers—are a class of nutrients belonging to the flavonoid family.

Polyphenols: a very broad class of substances that are structurally related.

There is always a phenolic acid group attached to one of the benzene rings in bioflavonoids, therefore all bioflavonoids are also referred to as ''polyphenols'' or ''phenols.'' (''Poly'' is from the Greek root which refers to ''more than one'' or ''many'' phenols.)

oligomeric Proanthocyanidins: colorless polyphenols that are referred to as oligomeric proanthocyanidins because the coloration towards red is their major trait of authentication from a chemical point of view. For example, when leaves naturally change from green to red in the fall, they transform colorless proanthocyanidins into colorful anthocyanidins.

They exist before or pro the anthocyanidins (the term ''before'' is synonymous with ''pro'' in Latin); hence the name, oligomeric proanthocyanidins.

Proanthocyanidins can be found in many plants, most notably pine bark, grape seed, and grape skin. However, bilberry, cranberry, black currant, green tea, black tea, and other plants also contain these flavonoids.

Nutritional supplements containing proanthocyanidins extracts from various plant sources are available, alone or in combination with other nutrients, in herbal extracts, capsules, and tablets.

The oxygen atom, which in a stable state has four pairs of electrons, becomes unstable when it loses an electron. An oxygen atom with seven electrons is referred to as a free radical. Free radicals quickly attach themselves to body tissues in order to stabilize themselves. The free radical takes an electron from the membrane of a body tissue and by doing so, produces yet another free radical, which then is obliged by its charge to seek out another electron - in your body.

What results is a cascade of oxidations - literally rusting body tissues...Free radical oxidation is a contributory factor in much chronic degenerative disease.

OPCs protect skin from sun damage. Many European skin creams feature grape seed extract as an aid to skin elasticity.

OPCs help keep collagen, elastin and hyaluronic acid healthy by blocking enzymes that disrupt their chemical structure.

This can be of profound use to theose who suffer from eczema and psoriasis.

OPCs prevent blood platelet stickiness better

Grapeseed grapes Grapes

OPCs prevent blood platelet stickiness better than aspirin, and thus can be of significant help to those with heart problems.

OPCs are commonly prescribed by physicians in Europe for various disorders that are likely to benefit from increased blood flow, such as diabetes, leg cramps and varicose veins.

OPCs support capillary strength.

Weak capillaries can contribute to bruising, elastin and collagen dysfunction, edema and circulatory insufficiencies.

Repeated double-blind tests have shown OPCs to quickly improve capillary strength in the elderly.

Human clinical studies show that 300 mg per day can quickly repair ruptured capillaries, thus alleviating water retention and such effects of edema as puffy eyes, swollen feet, and the bloating associated with premenstrual syndrome.

Grape seed extract improves blood flow in the eye's capillaries, and thus is prescribed for eye problems of the elderly, such as macular degeneration and cataracts.

By protecting immune cells against enzyme degradation, OPCs alleviate allergies and hayfever.

OPCs can also lower cholesterol and prevent LDL oxidation.

OPCs prevent LDL cholesterol oxidation better than vitamin C, and prevent bacteria from adhering to urinary tract membranes.

Grapeseed Grape Flower Buds

Grape seed extract provides potent antioxidants (oligomeric proanthocyanidins, monomeric polyphenols and flavonoids).

Grape Seed Extract provides a rich source of natural antioxidants.

Antioxidants help strengthen blood vessels and support the function of the eyes and immune system.

Polyphenols in grape seeds (Vitis vinifera), highly potent phyto-antioxidants that spare vitamin C, protect capillaries and promote cardiovascular health.

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Grape Seed

Grape seed extracts are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid, and OPCs. Typically, the commercial opportunity of extracting grape seed constituents has been for chemicals known as polyphenols, including oligomeric proanthocyanidins recognized as antioxidants.

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Potential anti-disease effects

Human case reports and results from laboratory and animal studies show that grape seed extract may be useful to treat heart diseases such as high blood pressure and high cholesterol. By limiting lipid oxidation, phenolics in grape seeds may reduce risk of heart disease, such as by inhibiting platelet aggregation and reducing inflammation. While such studies are promising, more research including long-term studies in humans is needed to confirm initial findings.

A polyphenol contained in grape seeds is resveratrol which may interfere with cancer cell growth and proliferation, as well as induce apoptosis, among a variety of potential chemopreventive effects.

Grape seed components may also be active against HIV by inhibiting virus expression and replication.

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Preliminary research shows that grape seed extract may have other possible anti-disease properties, such as in laboratory models of:

wound healing—grape seed proanthocyanidins induced vascular endothelial growth factor and accelerated healing of injured skin in mice.
tooth decay --seed phenolics may inhibit oral sugar metabolism and retard growth of certain bacteria causing dental caries.
osteoporosis -- grape seed extracts enhanced bone density and strength in experimental animals.
skin cancer -- grape seed proanthocyanidins decreased tumor numbers and reduced the malignancy of papillomas.
ultraviolet damage to skin—dietary proanthocyanidins may protect against carcinogenesis and provide supplementation for sunscreen protection.

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There is good evidence that grape seed extract can help treat chronic venous insufficiency and edema.

Currently, there are four clinical trials underway to assess the effect of grape seed extracts on human breast cancer, blood estrogen levels in postmenopausal women, and coronary artery disease.

Dosage, precautions and interactions

Oral grape seed extract is typically used as capsules or tablets usually containing 50 mg or 100 mg, or as a liquid to add drops to water and/or other drinks. Insufficient scientific information is known, however, about how long-term use of grape seed extract might affect health or any disease.

In a 12-month study, the safety of dietary intake of grape seed proanthocyanidins in a dose of 100 mg per kg per day was demonstrated in rodents.

The US National Center for Complementary and Alternative Medicine (NCCAM) reports that oral administration of grape seed extract was well tolerated in people over 8 weeks of a clinical trial.

Side Effects and Cautions. Other NCCAM advisories.

Grape seed extract is generally well tolerated when taken by mouth. It has been used safely for up to 8 weeks in clinical trials.
Side effects most often include headache, a dry, itchy scalp, dizziness or nausea
interactions between grape seed extract and medicines or other supplements have not been carefully studied

Due to the action of proanthocyanidins on limiting platelet adhesion, grape seed extract may increase the clotting time of blood.

Aromatase Inhibitor

Grape seed extract is also an aromatase inhibitor, i.e. it suppresses the conversion of testosterone to estradiol.

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Fat composition
Grape Seed Oil
Bottles of Grape seed oil
Saturated fats	Palmitic: 7% Stearic: 4%
Unsaturated fats	88%-90%
Monounsaturated fats	Oleic acid: 16-17%
Palmitoleic acid	<1%
Oleic acid	16%
Polyunsaturated fats	72-73%
Omega-3 fatty acids	α-Linolenic: <1%
Omega-6 fatty acids	Linoleic: 72%
Properties
Food energy per 100g	3,700 kJ (880 kcal)
Smoke point	216 °C (421 °F)
Iodine value	124-143
Saponification value	126 (NaOH) 180-196 (KOH)
Unsaponifiable	0.3% - 1.6%

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Grape seeds (Nr. 7 and 8) and grapes

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Read an article in Wikipedia with references and links Feb 11, 2011

* Grape seed extract. (2011, January 3). In Wikipedia,

The Free Encyclopedia. Retrieved 21:49, February 11, 2011, from

http://en.wikipedia.org/w/index.php?title=

Grape_seed_extract&oldid=405673814

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Grape Seed

Grape seeds are an excellent source of oligomeric proanthocyanidins (OPC's) and have been the subject of clinical research in France for their antioxidant activity.

Antioxidants play an important role in the development of collagen including skin, connective tissue and vascular walls.

Grape Seed extract provides antioxidant protection more effective than vitamins C and E, strengthens skin collagen, connective tissue and vascular walls and may be beneficial for diabetes, aging skin, colds and flu, prostate disease, psoriasis and multiple sclerosis.

Mother uses Grapseed oil for cooking and in her salads.

Sincerely, Mother

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See references for complete information including notes, comments, complete symptoms, sources, concerns and cautions.

Disclaimer :

In accordance with FDA regulation, we do not make any therapeutic claims for any Dietary Supplements in accordance with the Dietary Supplement Health and Education Act.

Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physicians, health care professional or other professional. You should not use the information on this website for diagnosing or treating any health problem, symptom or disease, prescribing any medication or other treatment, or in place of any other professional advice. This information is not intended to diagnose, treat, cure or prevent any diseases. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Your discretion is advised.

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