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Alternative Energy Accessories
The major compounds in shark cartilage are proteoglycans and glycoproteins (large molecules with protein and carbohydrate components), as well as protein and calcium salts. Shark cartilage is promoted mainly as an alternative to conventional cancer treatment, but some forms are being studied for use along with standard therapies. Continued Below |
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Quality Shark Cartilage from 'Mother Nature' |
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Country Life Shark Cartilage, 800 mg- 100 vegi cap
Super Potency Dietary Supplement |
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Shark Cartilage |
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Now Foods Shark Cartilage, 750 mg- 300 caps
NOW Shark Cartilage is derived from 100% pure, freeze dried backbone of sharks and is high in protein. It is high in protein. Our powder is thoroughly tested for important shark components and contains no solvents, bleaches, or chemical processing agents. The sharks that are harvested are also used for food purposes. |
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Solgar Solgars 100% Pure Australian Shark Cartilage - 750 mg- 90 caps
Solgar's advanced processed Shark Cartilage is 100% pure shark cartilage from Australia, renown for its strict and preogressive standards and regulations in the harvesting and processing of shark products for human consumption. Solgar's exclusive advanced process employs an all natural "next generation" technology that excludes the use of chemicals, radiation, ethylene oxide, bleach or excessive heat. This method results in a reduced odor and taste. |
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Shark Cartilage |
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Twinlab Advanced, Shark Cartilage Extract, 500 mg- 100 caps
Shark Cartilage naturally contains anti-angiogenesis factors, which while enhancing the immune system. Shark Cartilage 500 mg 100 capsules Twinlab. Supplement Facts: Serving Size: 1. Servings per Container: 100. Ingredient Amount Per Serving % Daily Value Shark cartilage concentrate (providing 275 mg purified shark cartilage) 500 mg **% Daily Value is based on a 2,000 calorie diet ** Daily Value not established. Cartilage (Bovine and Shark)What does it do? Cartilage, derived from shark and bovine (cow) sources, is a type of connective tissue comprised of mucopolysaccharides, protein substances, calcium, sulfur, and collagen. Early research in the 1950s and 1960s, using chips of bovine cartilage inserted into wounds, demonstrated that cartilage enhances wound healing.1 2 Since then, cartilage has been investigated for its potential role in regulating immune function and stopping the growth of tumors.3 The role of shark cartilage in inhibiting angiogenesis (the growth of new blood vessels) is hypothesized to be beneficial in halting the growth and spread of cancer.4 A few studies suggest that individuals with cancer may benefit from cartilage supplements;5 6 however, well-designed research is lacking, and many experts question the use of cartilage in this regard. A similar situation is seen with the use of cartilage in individuals with arthritis. Where is it found? Cartilage is derived from either sharks or cows. Cartilage has been used in connection with the following conditions (refer to the individual health concern for complete information): Who is likely to be deficient? Since it is not an essential nutrient, cartilage is not associated with deficiency states. How much is usually taken? Anyone who is interested in taking bovine or shark cartilage supplements should consult a nutritionally oriented doctor for advice. Are there any side effects or interactions? Reports have suggested that some people should not use a cartilage supplement. this concern is based only on theory, not clinical evidence. This would include those people with cardiovascular disease, women who are planning to be or are pregnant, nursing mothers, anyone having or having had surgery within thirty days, and athletes training intensely. None of these contraindications has been proven, however. The calcium in the huge amount of shark cartilage taken by some people with cancer (greater than 50 grams per day) could lead to toxicity. However, remarkably few instances of actual calcium toxicity have been reported.At the time of writing, there were no well-known drug interactions with cartilage.References:1. Prudden JF, Allen J. The clinical acceleration of healing with a cartilage application. JAMA 1965;192:352, 56.2. Prudden JF, Wolarsky E. The reversal by cartilage of the steroid-induced inhibition of wound healing. Surg Gyn Obstet 1967;125(7):109, 13.3. Prudden JF. The treatment of human cancer with agents prepared from bovine cartilage. J Biol Res Mod 1985;4:551?84.4. Lee A, Langer R. Shark c |
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Quality Shark Cartilage from 'House Of Nutrition' |
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Country Life's Biochem Shark Cartilage 800mg 50Caps
Country life SHARK CARTILAGE CAPSULES 800 MG 50caps. |
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Shark Cartilage |
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Douglas Lab's Shark Cartilage 740 mg 100 caps
Shark Cartilage 100 capsulesEach Capsule Contains: Shark Cartilage Freeze-dried (vacuum process) physically processed Shark Cartilage 740 mg. Other ingredients: Gelatin, cellulose, vegetable stearate and silicaSuggested Usage:Adults take 1 capsule for every 11 pounds of body weight for the first 3 weeks-NOT TO EXCEED 18 CAPSULES DAILY. Take in equal amounts 15 minutes before meals. Thereafter take 4 to 6 capsules daily or as directed by physician. |
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Shark Cartilage |
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Futurebiotics Shark Cartilage 100Caps
Product Description: The shark is one of the most remarkable creatures on the face of the earth. Existing virtually unchanged for 250 million years, shark's are unique in that they have a natural immunity to almost every disease known to man. When a shark is wounded, it heals quickly. The shark is the only animal with a skeleton comprised entirely of cartilage which accounts for between 6 and 8% of its body weight. Rich in mucopolysaccharides, each 750 mg capsule contains only pure Pacific shark cartilage with no additives, fillers or binders. Serving Size:3, 33 servings per container. Contains: 100% Pure Shark Cartilage with no additives or fillers. The powder is a naturally off-white color and contains 40-45% Protein. Mucopolysaccharides. Other Ingredients :Gelatin, Water. Suggested Use: As a dietary supplement for adults, take 3 capsules before meals 3 times daily or as recommended by a healthcare professional. Does Not Contain: yeast, salt, sugar, starch, wheat, gluten, soy, corn, dairy, artificial preservatives or colorings. Warnings/Cautions: Do not use if you are pregnant or nursing, recovering from a heart - circulatory condition, or have had serious surgery within a month's time. Keep cool, dry and away from direct light. Keep out of reach of children. Supplement Facts: Serving Size is 3. Amount Per Serving %DV Calories 12- * Protein 3g 6% Calcium 1000mg 100% Phosphorus 500mg 50% *Daily Value (DV) not established. |
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Kal's Shark Cartilage 750mg 30Caps
Kal's Shark Cartilage 750mg 30Caps |
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Now's Shark Cartilage 750mg Freeze Dried 100Caps
NOW Shark Cartilage is derived from 100% pure, freeze dried backbone of sharks. It is high protein. Our powder is thoroughly tested for important shark components and contains no solvents, bleaches, or chemical processing agents. Serving Size: 6 capsules. Suggested Use: As a dietary supplement, take 6 capsules 1-2 times daily. Free of: sugar, salt, starch, yeast, wheat, corn, soy, egg, milk. Other Ingredients: stearic acid. Warnings: None. Disclaimers: None. |
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Shark Cartilage |
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Olympian Labs Shark Cartilage 100Caps
Olympian Labs Shark Cartilage 100Caps |
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Solgar Solgar Shark Cartilage 750mg 45Caps
Product Information: Supplement Facts. Serving Size 8. Servings Per Container 45 Capsules. Amount Per Serving % DailyValue Calories 10 N/A* Cholesterol 5 Gm 2% Total Carbohydrate 1 Gm N/A* Protein 2 Gm 4% Calcium 1000 Mg 100% Phosphorus 540 Mg 54% Magnesium 16 Mg 4% Sodium 85 Mg 4%* Daily value not established. Directions: As a dietary supplement for adults, eight (8) capsules daily. May be distributed throughout the day, between meals or as directed by a healthcare practitioner. Other Ingredients: Shark cartilage, vegetable cellulose, vegetable magnesium stearate, vegetable glycerin, water. Does Not Contain: Sugar, corn, yeast, wheat, soy, dairy products, preservatives, artificial flavors or colors. Warnings: To assure freshness and potency, store in a cool, dry place, away from heat, light and moisture. Keep out of reach of children. If you are pregnant, nursing, recovering from surgery, have a heart/circulatory problem or are considering exceeding the suggested use, please consult your healthcare practitioner. |
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Shark Cartilage |
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Source Naturals Cartilade® Shark Cartilage 740mg 50Caps
Shark cartilage has long been valued by traditional herbalists in China, where it has been consumed for centuries as shark fin soup. Shark cartilage contains mucopolysaccharides, a family of complex carbohydrates including the now well-known chondroitin sulfate. It is an excellent source of calcium and phosphorus. Supplement Facts for caps: serving size: 6 capsules. Amount %DV Phosphorus 400 mg, Magnesium 12 mg, Zinc 0.5 mg, Shark Cartilage 4.44 g. Other Ingredients: capsule (glycerine and gelatin), dibasic calcium phosphate, magnesium stearate, modified cellulose gum, stearic acid, and colloidal silicon dioxide. Suggested Use: Take two capsules before meals 3 times a day. Warning: If you are pregnant or breastfeeding, recovering from recent surgery or have a heart/circulatory condition, consult your health care professional before using this product. Warning: If you are pregnant, breast-feeding, recovering from recent surgery or have a heart/circulatory condition, con-sult your health care professional before using this product. |
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Shark Cartilage |
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TwinLab's Advanced Shark Cartilage 500mg 100Caps
Description Standardized For Protein And Mucopolysaccharides Each capsule contains only the highest quality shark cartilage extract obtainable, imported from Japan. The shark cartilage concentrate is encapsulated at our own state of the art facilities with stringent quality control assuring correct potencies and outstanding produce freshness. Each serving of 2 capsules provides: Ingredient Amount US RDA Shark Cartilage Concentrate (standardized for 24% protein and 20% mucopolysaccharides) 1000 mg. Other ingredients: Dextrin, Gelatin, Purified Water, MCT, Silica, Magnesium Stearate. Directions As a dietary supplement, take 2-5 capsules daily or as directed by a physician. Disclaimer Statements contained herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication. |
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Homeopathic Remedies 
RemediesShark Cartilage
Shark cartilage is a dietary supplement made from the dried and powdered cartilage of a shark; that is, from the tough material that composes a shark's skeleton. Shark cartilage is claimed to combat and/or prevent a variety of illnesses, most notably cancer. It is often marketed under the names Carticin, Cartilade, or BeneFin. A derivative of it named Neovastat was tested by AEterna Zentaris as an angiogenesis inhibitor and showed promising results in animals. Two clinical trials of Neovastat were completed in 2007, showing negative results.
The benefits of this supplement have not been scientifically proven, nor has shark cartilage been reviewed by the U.S. Food and Drug Administration (FDA). However, its pervasive use is due to the incorrect notion that sharks do not get cancer. This idea became popular with the best-selling book Sharks Don't Get Cancer by Dr. William Lane, published in 1992. This assertion even appears in the film on sharks at the Monterey Bay Aquarium (although the aquarium does not endorse the use of shark cartilage).
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Read the Current article in Wikipedia with references and links October 16, 2010
* Shark cartilage. (2010, May 16). In Wikipedia,
The Free Encyclopedia. Retrieved 05:36, October 16, 2010, from
http://en.wikipedia.org/w/index.php?title
=Shark_cartilage&oldid=362378157
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Read the entire article at cancer.org
Shark Cartilage
Other common name(s): Carticin, Cartilade™, BeneFin™, Neovastat (AE-941)
Scientific/medical name(s): none
Description
Shark cartilage is extracted from the heads and fins of sharks. Cartilage is a type of connective tissue that is found in the skeletal systems of many animals, including humans. Sharks' skeletons are made up almost entirely of cartilage. The major compounds in shark cartilage are proteoglycans and glycoproteins (large molecules with protein and carbohydrate components), as well as protein and calcium salts. Shark cartilage is promoted mainly as an alternative to conventional cancer treatment, but some forms are being studied for use along with standard therapies.
Overview
Most shark cartilage products are sold as dietary supplements in the form of pills or powders. Most have not been tested for effectiveness, safety, or to verify the purity of ingredients. Available scientific evidence does not support claims that shark cartilage supplements sold as food supplements are an effective treatment for cancer, osteoporosis, or any other disease. One shark cartilage product, called AE-941, is in the early phases of development as an investigational new drug.
Although some laboratory and animal studies have shown that some components in shark cartilage have the ability to slow the growth of new blood vessels, these effects have not been proven in humans. The few small clinical studies of shark cartilage products published to date have not shown any benefit against cancer. Further clinical trials of the supplements and of a purified cartilage extract are currently under way.
How is it promoted for use?
Supporters believe that shark cartilage supplements or cartilage from other animals, such as cows, can slow or stop the growth of cancer (see also Bovine Cartilage). According to its supporters, shark cartilage contains proteins that stop angiogenesis, the process of blood vessel development. Tumors need a network of blood vessels to survive and grow, so cutting off the tumor's blood supply starves it of nutrients, causing it to shrink or disappear. Some supporters also claim that shark cartilage can help against other diseases such as osteoporosis, arthritis, psoriasis, macular degeneration, and inflammation of the intestinal tract.
What does it involve?
Shark cartilage is usually taken by mouth as a capsule, powder, or liquid extract, but some people have trouble taking it by mouth because of the strong fishy smell and taste. It is sometimes used as an enema. The dose and length of treatment varies widely. Manufacturers often recommend large doses (up to 1 cup a day). Chondroitin, a supplement often used with glucosamine to help arthritis, is also made from cartilage. Either bovine or shark cartilage may be used to produce chondroitin.
Shark cartilage dietary supplements are different from AE-941, a liquid shark extract known as Neovastat. This extract is regulated by the U. S. Food and Drug Administration (FDA) as an investigational new drug. AE-941 is being used in carefully controlled clinical trials for people who have agreed to be part of the study.
What is the history behind it?
A New York surgeon named John Prudden began investigating the use of animal cartilage as a medical treatment in the early 1950s. He used powdered cow cartilage to help heal the wounds of surgical patients and later used it to treat cancer. He reported that tumors shrank in more than half of the patients he treated, but the results have not been repeated in other studies.
Since then, many kinds of cartilage, from animals such as pigs, sheep, chickens, cows, and sharks, have been studied. After the 1992 publication of a popular book titled Sharks Don't Get Cancer, written by I. William Lane, PhD, shark cartilage supplements became very popular among people interested in alternative medicine. The idea was that since cancer does not seem to develop in sharks as much as in humans, there may be something in the sharks' systems that protects them from the disease.
Interest in shark cartilage increased after a television news magazine aired a segment in 1993 showing a study of patients with advanced cancer in Cuba who had gone into remission after being treated with shark cartilage. The results, however, have not been published in a peer-reviewed medical journal. The National Cancer Institute (NCI) later concluded that the results of the Cuban study were "incomplete and unimpressive."
According to the FDA and the Federal Trade Commission, some manufacturers of shark cartilage supplements have been fined and/or forced to remove their products from the market for making unproven claims that they have cancer-fighting abilities. Such claims can only be made for drugs with proven effects.
Finding drugs that halt the spread of cancer by stopping the growth of blood vessels has been the subject of many conventional research studies in recent years. Some researchers believe that this therapy, called anti-angiogenesis therapy, holds a great deal of promise for certain types of cancer. A number of anti-angiogenesis drugs are currently being studied, and one is already approved to treat certain types of cancer. In addition, several drugs that were approved for other uses, including cancer treatment, have anti-angiogenic effects. These are now being studied more carefully for their role in anti-angiogenesis. Some researchers are trying to purify compounds in cartilage that stop the growth of blood vessels. But the most promising anti-angiogenic substances now in existence are those that have been purified from sources other than cartilage or have been made in laboratories.
What is the evidence?
The consensus of available scientific evidence does not support claims that whole shark cartilage supplements are an effective treatment for cancer in humans. Although studies using cow and shark cartilage in people with cancer began in the early 1980s, few have been published. The scientific truth of many of these studies is open to question because they do not describe how treatment was given, how patients were assessed, long-term survival outcomes, or information about the cartilage used and its components.
Some experiments have shown that some forms of shark cartilage possess a modest ability to slow the growth of new blood vessels in laboratory cell cultures and in animals, but the effects on humans are not known. According to one review, results from 9 clinical series of patients receiving shark cartilage were mixed. None of the series were done under strict scientific controls.
In one clinical trial involving about 50 patients, researchers concluded that shark cartilage supplements had no effect on patients with advanced-stage cancers. When a more recent placebo-controlled clinical trial tested shark cartilage in more than 80 patients with advanced cancer, no benefit was found. "It wasn't well tolerated, there wasn't any suggestion of benefit in terms of quality of life, there wasn't any suggestion of benefit in terms of survival," commented Charles L. Loprinzi, the physician who authored the study report.
Researchers generally agree that the protein molecules in shark cartilage may be too large to be absorbed by the digestive tract and are simply excreted without ever reaching tumors in the body. However, some scientists have suggested that these substances may be more readily absorbed when taken in a liquid form. One study concluded that the liquid shark cartilage extract AE-941 (Neovastat) taken by mouth effectively slowed the growth of new blood vessels in healthy men, suggesting to the study authors that the active ingredients in liquid shark cartilage were available for use by the body's healing systems.
A small study of the extract found that larger doses were better than smaller doses at prolonging survival in patients with advanced kidney cancer. A larger study was then done. While the results of this study have not been published, the manufacturer has stopped testing it against kidney cancer, suggesting that the results may not have been positive. The NCI sponsored a large, placebo-controlled randomized clinical trial using the extract with conventional chemotherapy and radiation therapy for the treatment of advanced (stage III) lung cancer. Preliminary results in this study were reported at the 2007 meeting of the American Society of Clinical Oncology. Based on analysis of outcomes from 379 patients, the researchers concluded that AE-941 did not improve overall survival.
Are there any possible problems or complications?
This product is sold as a dietary supplement in the United States. Unlike drugs (which must be tested before being allowed to be sold), the companies that make supplements are not required to prove to the Food and Drug Administration that their supplements are safe or effective, as long as they don't claim the supplements can prevent, treat, or cure any specific disease.
Some such products may not contain the amount of the herb or substance that is written on the label, and some may include other substances (contaminants). Actual amounts per dose may vary between brands or even between different batches of the same brand.
Most such supplements have not been tested to find out if they interact with medicines, foods, or other herbs and supplements. Even though some reports of interactions and harmful effects may be published, full studies of interactions and effects are not often available. Because of these limitations, any information on ill effects and interactions below should be considered incomplete.
Shark cartilage is not thought to be toxic, although it has been known to cause nausea, indigestion, fatigue, fever, and dizziness in some people. It may affect liver function, so ask your doctor before taking it if you have any kind of liver disease. It may also slow down the healing process for people recovering from surgery. People with a low white blood cell count should not take shark cartilage enemas, because there is a risk of life-threatening infection. Children should not take it because it could interfere with body growth and development.
Allergic reactions are possible. People with seafood allergies should avoid shark cartilage and chondroitin that is made from it. Women who are pregnant or breast-feeding should also avoid these supplements.
It is not known whether shark cartilage could cause any problems from interactions with other medicines. Relying on this type of treatment alone and avoiding or delaying conventional medical care for cancer, may have serious health consequences.
Additional resources
More information from your American Cancer Society
The following information on complementary and alternative therapies may also be helpful to you. These materials may be found on our Web site (www.cancer.org) or ordered from our toll-free number (1-800-ACS-2345).
Guidelines for Using Complementary and Alternative Therapies
Dietary Supplements: How to Know What Is Safe
The ACS Operational Statement on Complementary and Alternative Methods of Cancer Management
Complementary and Alternative Methods for Cancer Management
Learning About New Ways to Treat Cancer
Learning About New Ways to Prevent Cancer
References
Batist G, Patenaude F, Champagne P, et al. Neovastat (AE-941) in refractory renal cell carcinoma patients: report of a phase II trial with two dose levels. Ann Oncol. 2002;13:1259-1263.
Berbari P, Thibodeau A, Germain L, et al. Antiangiogenic effects of the oral administration of liquid cartilage extract in humans. J Surg Res. 1999;87;108-113.
Ebube NK, Mark W, Hahm H. Preformulation studies and characterization of proposed chondroprotective agents: glucosamine HCl and chondroitin sulfate. Pharm Dev Technol. 2002;7:457-469.
Ernst E, Cassileth B. How useful are unconventional cancer treatments? Eur J Cancer. 1999;35:1608-1613.
Federal Trade Commission. FTC v Heritage Health Products Company (suit filed April 16, 2004). Accessed at: www.ftc.gov/os/caselist/heritagehealth/040427stipheritagehealth.pdf on June 11, 2008.
Federal Trade Commission. Complaints. Accessed at: www.ftc.gov/os/1998/09/9723071.cmp.htm, www.ftc.gov/os/1999/09/bodysystemcmp.htm, and www.ftc.gov/os/2001/08/formorcmp.htm on July 11, 2007.
Finkelstein JB. Sharks do get cancer: few surprises in cartilage research. J Natl Cancer Inst. 2005;97:1562-1563.
Food and Drug Administration. Company ordered to halt sales of unapproved drugs, reimburse buyers. FDA Consumer Magazine, September-October 2004. Accessed at: www.fda.gov/fdac/departs/2004/504_upd.html#sales on June 11, 2008.
Loprinzi CL, Levitt R, Barton DL, et al, and the North Central Cancer Treatment Group. Evaluation of shark cartilage in patients with advanced cancer: a North Central Cancer Treatment Group trial. Cancer. 2005;104:176-182.
Lu C, Lee JJ, Komaki R, et al. A phase III study of Æ-941 with induction chemotherapy (IC) and concomitant chemoradiotherapy (CRT) for stage III non- small cell lung cancer (NSCLC) (NCI T99-0046, RTOG 02-70, MDA 99-303). J Clin Oncol, 2007 ASCO Annual Meeting Proceedings Part I. Vol 25, No. 18S (June 20 Supplement), 2007: 7527.
Medline Plus. Herbs and supplements: Shark cartilage 2006. Available at: www.nlm.nih.gov/medlineplus/druginfo/natural/patient-sharkcartilage.html. Accessed July 11, 2007. Content no longer available.
Memorial Sloan-Kettering Cancer Center. About herbs: Shark cartilage. 2006. Accessed at: www.mskcc.org/mskcc/html/69374.cfm on June 11, 2008.
Miller DR, Anderson GT, Stark JJ, Granick JL, Richardson D. Phase I/II trial of the safety and efficacy of shark cartilage in the treatment of advanced cancer. J Clin Oncol. 1998;16:3649-3655.
Ostrander GK. Cheng KC. Wolf JC. Wolfe MJ. Shark cartilage, cancer and the growing threat of pseudoscience. Cancer Research. 2004;64:8485-8491.
National Cancer Institute Physician Data Query (PDQ). Cartilage (Bovine and Shark). 2006. Accessed at: www.cancer.gov/cancertopics/pdq/cam/cartilage/healthprofessional on June 11, 2008.
Raloff J. A fishy therapy: A thriving but controversial dietary supplement. Science News Online. 2005; 167(10):154. Accessed at: www.sciencenews.org/articles/20050305/bob9.asp on July 11, 2007. Content no longer available.
Note: This information may not cover all possible claims, uses, actions, precautions, side effects or interactions. It is not intended as medical advice, and should not be relied upon as a substitute for consultation with your doctor, who is familiar with your medical situation.
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In accordance with FDA regulation, we do not make any therapeutic claims for any Dietary Supplements in accordance with the Dietary Supplement Health and Education Act.
Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physicians, health care professional or other professional. You should not use the information on this website for diagnosing or treating any health problem, symptom or disease, prescribing any medication or other treatment, or in place of any other professional advice. This information is not intended to diagnose, treat, cure or prevent any diseases. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Your discretion is advised.
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